Walk, don't run to implement SPRINT findings in primary care
Medicine

Walk, don't run to implement SPRINT findings in primary care


My latest Medscape commentary concerns the primary care implications of the SPRINT trial of lower systolic blood pressure goals in patients at high risk for cardiovascular disease, whose initial findings appeared last week in the New England Journal of Medicine. My bottom line for clinicians is: don't throw out the JNC 8 guideline and blood pressure targets just yet. Here's a representative excerpt from the commentary:

It's worth noting that the SPRINT results do not completely upend JNC 8. SPRINT focused on an especially high-risk population of adults with hypertension who were aged 50 years or older and had an average Framingham risk score of 20%. Patients with diabetes or a history of a stroke were not included. According to a companion study published in the Journal of the American College of Cardiology, only 1 in 6 US adults currently receiving blood pressure treatment would have been eligible to participate in this trial. Until new treatment guidelines emerge, I think it is premature to extrapolate these findings to the majority of patients at lower cardiovascular risk—and therefore less likely to benefit—but equally vulnerable to the increased adverse effects observed in this study.

Another key point: The way that blood pressures were measured in this study is probably not the way they are measured in your offices. Although best practice guidelines suggest that patients should be seated and at rest for at least 5 minutes before blood pressure is measured, you and I know all too well how rarely this occurs when patients arrive late or we are running behind schedule.

Recognizing that blood pressures obtained in the office are often inaccurate, the US Preventive Services Task Force and the Community Preventive Services Task Force recommend confirming office measurements with self-measured blood pressure monitoring before starting or adjusting medications. In order to make this practice possible, and to implement lower blood pressure goals in selected patients without overtreating them, insurers absolutely must cover patients' purchase of validated blood pressure monitors and pay family physicians for the extra time it takes to make medication adjustments outside of office visits.




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